"Mess Around" by Ray Charles

Ray Charles (aka The Genius) was one of the biggest superstars of the 60s, ranking at #3 for the decade according to Joel Whitburn's Top Pop Singles. The same book also ranked him as the 18th most successful artist of all-time.

Before his career kicked into high gear with the #6 smash in 1959, "What'd I Say", Ray Charles did a rousing version of "Mess Around" in 1953. It didn't chart, but has become a classic nonetheless. The tune was also famously featured in a memorable scene from the 80s movie, Planes, Trains, and Automobiles.